Endocrine Abstracts

Introduction: Primary hyperparathyroidism is frequent; it can be ectopic in 11 to 25% of cases, the mediastinal position is the most frequent ectopic position, but the intrapericardial position is exceptional.Clinical Case: A 58 year old woman with primary hyperparathyroidism complicated by severe osteoporosis. The CT scan and parathyroid scintigraphy reveals a 17 mm parathyroid adenoma in the mediastinal aortopulmonary position. After a first thoracic s...

Introduction: Tuberculosis is a granulomatosis with systemic manifestations. Pulmonary involvement is usually in the foreground. Rarely, hypercalcaemia initiates the pathology. The incidence of hypercalcaemia in tuberculosis varies according to studies and regions between 2 and 25%, with the highest incidences in the most isolated countries and those with the highest calcium and vitamin D intakes.Clinical Case: This is the case of our patient known for b...

Although rare in children, Graves’ disease remains the major cause of hyperthyroidism. Positive diagnosis is easy, but management can be extremely problematic.Case Report: We report the case of a 13 year old female patient treated for Graves’ disease since 4 years; non compliant to treatment; after adjustment of therapy and achievement of euthyroidism; a surgical cure is programmed. 24 hours after surgery, severe hypocalcaemia appeared, requiri...

Introduction: The treatment of prolactin adenomas is medical based on the use of dopaminergic agonists but the presence of an underlying valvulopathy makes the treatment by cabergoline delicate.Clinical case: We report the case of a 60 year old female patient, operated on for aortic valve disease, with moderate mitral leakage. On the occasion of a decrease in visual acuity; a prolactin macro adenoma is diagnosed In agreement with the cardiologist; we opt...

Introduction: The most frequent cystic lesions in the pituitary region are: cystic adenomas, Rathke’s pouch cysts and craniopharyngiomas. But sometimes the diagnosis can be difficult.Clinical case: This is the case of a women patient who consulted at the age of 20 for a pituitary cystic process revealed by secondary amenorrhoea; evoking in the first place a Rathke’s pouch cyst. Hormonal assessment reveals tumour-related hyperprolactinemia; the ...

Introduction: Maccune albright syndrome; is a rare disorder resulting from the involvement of several organs; the phenotype is variable depending on the clinical manifestations linked to the importance of the tissues affected by the mutation.Case report: In our patient, the diagnosis was not made until she was 8 years old, despite some suggestive signs: as café au lait skin macules at birth and early forearm bone fractures at the age of 3 years. At ...

Introduction: Cushing’s disease is defined as hypercortisolism caused by excessive secretion of ACTH from a pituitary adenoma. Cushing’s disease is a rare entity in childrenObservation: We report the case of 3 children with Cushing’s disease including 2 boys and 1 girl, the mean age at the diagnosis was 12.6 years. Clinically, weight gain was constant in all children, a delay in statural growth was noted in 2 children, signs of catabolism ...

Introduction: The incidence of thyroid cancers is increasing; they are considered to have a very good prognosis with good survival The frequency of metastases is 5 to 10%. The most common locations are lung and bone. The morbidity of metastatic disease is related to the initial histological type, tumour mass, location of metastases, age, possible loss of iodine uptake and 18F-FDG uptakeMaterials and methods: We collected 25 patients treated for hormone-d...